【NeuroNexus客户文章】V1 CONTEXTUAL RESPONSES DEPEND ON PERCEPTUAL ORGANIZATION

Lisa Kirchberger et al. with Pieter Roelfsema’s group at the Netherlands Institute for Neuroscience used NeuroNexus A1x32-5mm-25-177-A32 acute probes localized by current source density analysis (CSD) in primary visual cortex (V1) of awake behaving mice. The laminar probe spanned the layers of V1 and recorded multi-unit activity, MUA, as well as individual units for receptive field (RF) characterization. Their results in Science Advances address cortical responses to contextual information outside the RF, which were most driven by disinhibitory VIP neurons and play a role in figure perception. 


Lisa Kirchberger等人和荷兰神经科学研究所的Pieter Roelfsema小组使用NeuroNexus A1x32-5mm-25-177-A32急性电极,通过电流源密度分析(CSD)在清醒行为小鼠的初级视觉皮层(V1)中定位。层流探针跨越V1层,记录多单位活动,MUA,以及感受野(RF)特征的单个单位。他们在科学进展的研究结果解决了大脑皮层对射频外部环境信息的反应,这种反应主要由去抑制VIP神经元驱动,并在图形感知中发挥作用。


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